Design of Organometallic Molecules and Applications
(DOGMA)
The group Design of Organometallic Molecules and Applications was established by the end of 2016 at the Institute of Chemical Research in Sevilla (Spain), a mixed research center CSIC-University of Sevilla. We are currently located in the new building at lab203.
The primary aim of our research team is to synthesize organometallic molecules with specific electronic and steric properties enabling the activation and functionalization of different types of bonds. We are interested in developing new efficient catalysts, with a important effort in the understanding of the mechanisms by which the metal complexes operate. Also, we focuse on fundamental aspects elucidating the detailed electronic structure and reactivity patterns of the organometallic molecules. As such, our research program spans the areas of organic synthesis, catalysis, and organometallic chemistry. Currently, we are dealing with group 10 transition metals (mainly nickel and platinum) stabilized by pincer bis(phosphino)boryl and N-heterocyclic carbene ligands and exploring their potential in carbon dioxide transformation and dehydrocoupling processes leading to B-N, Si-N, C-Si and C-B bonds.
Furthermore, we are currently dealing with the synthesis of metal nanoparticles of gold and platinum and their potential use in catalysis.
Lab 203
THE GROUP
Present Members
Salvador Conejero
Research Scientist -CSIC
Amor Rodríguez
Tenured Scientist -CSIC
Pablo Ríos
Associate professor
Orestes Rivada Wheelaghan
Ramón y Cajal researcher
Carlos J. Laglera Gándara
Postdoctoral researcher
Carlos García Bellido
Postdoctoral researcher
Juan Alfredo Cayuela Castillo
PhD student
Natalia Salas León
PhD student
Miguel Ángel Martín Neri
PhD student
Carlos Martínez Ceberio
PhD student
Past Members
Leonardo C. Moraes (PhD Thesis, 2018)
Hugo Fouilloux (internship from École Polytechnique, Paris) (2015)
Marta Roselló Merino (PhD thesis, 2013)
José Antonio Fernández Molina (Technician, 2018)
Lucía Álvarez Rodríguez (posdoctoral researcher)
Julián Jiménez Pérez (Master degree, University of Sevilla)
Andrea Jurado Escribano (Master degree, University of Sevilla)
Marina Barturen (Master degree, University of Sevilla)
Macarena Garcia Ayala (Master degree, University of Sevilla)
Raquel J. Rama (internship from the University of Sevilla)
Félix León (internship from the University of Sevilla)
RESEARCH
Research in the group of Design of Organometallic Molecules and Applications is focused on three main topics:
1. Low-electron count platinum complexes stabilized by N-heterocyclic carbenes
During the last years we have been involved in the isolation of stable, yet reactive, cationic Pt(II) 14-electron species making use of the excellent stereoelectronic properties of N-heterocyclic carbene ligands. The reactivity of these compounds has allowed to synthesize unusual platinum complexes in the oxidation state +3 and +4.
14-electron Pt(II) complexes interact with dihydrogen, boranes and silanes to form sigma-complexes that can undergo further reactivity in catalytic reactions
2. Nickel complexes bearing bis(phosphino)boryl pincer ligands.
This project is focused on a rational design, by means of using pincer-like ligands based of diphosphinoboryls (PBP), of group 10 metal catalysts able to promote different catalytic transformations that include small molecules activation (H2, CO2, boranes,…). An important part of our research is the investigation of the mechanisms that operate in this transformations and the influence of the boryl group in this processes.
3. Synthesis of metal nanoparticles
In the last few years we have been involved in a new research program aim at the synthesis of metal nanoparticles stabilized by N-heterocyclic carbene ligands and by N-heterocyclic thiones. Part of the research has been carried out in collaboration with the groups of Bruno Chaudret (Laboratoire de Physique et Chimie des Nano-Objets, Toulouse) and Karine Philippot (Laboratoire de Chimie de Coordination, CNRS, Toulouse).
PUBLICATIONS
Some selected publications:
Electrophilic Hydrosilylation of Electron-Rich Alkenes Derived from Enamines
Carlos J. Laglera-Gándara, Julián Jiménez-Pérez, Francisco J. Fernández-de-Córdova, Pablo Ríos, Salvador Conejero
Angew. Chem. Int. Ed. 2024, DOI: /10.1002/anie.202404859.
Pablo Ríos, Matthew S. See, Rex C. Handford, Jason K. Cooper, T. Don Tilley
Angew. Chem. Int. Ed. 2023, DOI: /10.1002/anie.202310307.
Cleavage of Carbon Dioxide C=O Bond Promoted by Nickel-Boron Cooperativity in a PBP-Ni Complex
Lucía Álvarez-Rodríguez, Pablo Ríos, Carlos J. Laglera-Gándara, Andrea Jurado, Francisco José Fernández de Córdova, T. Brent Gunnoe, Amor Rodríguez
Angew. Chem. Int. Ed. 2023, 62, e202306315.
Ethylene dimerization and oligomerization using bis(phosphino)boryl supported Ni Complexes
Fanji Kong, Pablo Ríos, Conno Hauck, Francisco José Fernández de Córdova, Diane A. Dickie, Laurel G. Habgood, Amor Rodríguez, T. Brent Gunnoe
J. Am. Chem. Soc. 2023, 145, 179-193.
Electrocatalytic CO2 reduction with a binuclear bis-terpyridine pyrazole-bridged cobalt complex
Antoine Bohn, Juan José Moreno, Pierre Thuéry, Marc Robert, Orestes Rivada–Wheelaghan
Chem. Eur. J. 2023, 29, e202202361.
σ-GeH and Germyl Cationic Pt(II) Complexes
Carlos J. Laglera-Gándara, Pablo Ríos, Francisco José Fernández-de-Córdova, Marina Barturen, Israel Fernández, Salvador Conejero
Inorg. Chem. 2022, 61, 20848-20859.
(Article Selected as Front Cover)
Bonding Situation of σ-E−H Complexes in Transition Metal and Main Group Compounds
Pablo Ríos, Salvador Conejero, Israel Fernández
Chem. Eur. J. 2022, 28, e202201920.
Hugo Fouilloux, Marie-Noelle Rager, Pablo Ríos, Salvador Conejero, Christophe M. Thomas
Angew Chem. Int. Ed. 2022, 61, e202113443.
Hydrosilylation of Carbonyl Compounds Catalyzed by a Nickel complex bearing a PBP-ligand
Jose Antonio Fernández, Juan Manuel García, Pablo Ríos, Amor Rodríguez
Eur. J. Inorg. Chem. 2021, 2993-2998.
Article for the special collection for GEQO and RSEQ prize winners:
Ligand Effects in Carbon-Boron Coupling Processes Mediated by σ-BH Platinum Complexes
Eur. J. Inorg. Chem. 2021, 3528-3539.
Article for the special collection for GEQO and RSEQ prize winners selected for the Front Cover:
Ambiphilic Boryl Groups in a Neutral Ni(II) Complex: A New Activation Mode of H2
Pablo Ríos, Francisco José Fernández-de-Córdova, Javier Borge, Giuseppe Sciortino, Agustí Lledos and Amor Rodríguez
Reversible carbon–boron bond formation at platinum centers through σ-BH complexes
Chem. Sci. 2021, 12, 1647-1655.
(Article Selected as Pick of the Week and Front Cover)
Enhancing the catalytic properties of well-defined electrophilic platinum complexes
Pablo Ríos, Amor Rodríguez and Salvador Conejero
Chem. Commun. 2020, 56, 5333-5349.
σ-Silane Platinum(II) Complexes as Intermediates in C−Si Bond Coupling Processes
Pablo Ríos, Hugo Fouilloux, Pietro Vidossich, Josefina Díez, Agustí Lledós, Salvador Conejero
Ligand Effects on the Selective Hydrogenation of Nitrobenzene to Cyclohexylamine Using Ruthenium Nanoparticles as Catalyst
M. Rosa Axet, Salvador Conejero, Iann C. Gerber
Platinum Complexes with a Phosphino‐Oxime/Oximate Ligand
Javier Francos, Javier Borge, Salvador Conejero, Victorio Cadierno
Eur. J. Inorg. Chem. 2018, 3176-3186.
Isolation of a Cationic Pt(II) σ-Silane Complex
Pablo Ríos, Hugo Fouilloux, Pietro Vidossich, Josefina Díez, Agustí Lledós, Salvador Conejero
Selective Catalytic Synthesis of Amino-Silanes at Part-per Million Catalyst Loadings
Pablo Rios, Marta Rosello-Merino, Orestes Rivada-Wheelaghan, Javier Borge, Joaquin Lopez-Serrano, Salvador Conejero
Stabilisation of gold nanoparticles by N-heterocyclic thiones
Leonardo C. Moraes, Bertrand Lacroix, Rute C. Figueiredo, Patricia Lara, Javier Rojo, Salvador Conejero
Cationic Platinum(II) sigma-Silane complexes in Carbon Dioxide Hydrosilation
Pablo Ríos, Josefina Díez, Joaquín López-Serrano, Amor Rodríguez, Salvador Conejero
Pablo Ríos, Joaquín López-Serrano, Amor Rodríguez
Catalytic dehydrocoupling of amine-boranes and amines into diaminoboranes. Isolation of a Pt(II), Shimoi-type, eta1-BH complex
Marta Roselló-Merino, Raquel J. Rama, Josefina Díez, Salvador Conejero
Chem. Commun. 2016, 52, 8389.
Selective reduction of carbon dioxide to bis(silyl)acetal catalyzed by a PBP-supported nickel complex
Pablo Ríos, Natalia Curado, Joaquín López-Serrano, Amor Rodríguez
Chem. Commun. 2016, 52, 2114.
NHC-Stabilized Ru Nanoparticles: Synthesis and Surface Studies
P. Lara, L. M. Martínez-Prieto, M. Roselló-Merino, C. Richter, F. Glorius, S. Conejero, K. Philippot, B. Chaudret
Nano-Struct. Nano-Objects, 2016, 6, 39.
Hydride Ligands Orbiting around Low-Coordinate Metal Centres
Manuel A. Ortuño, Pietro Vidossich, Salvador Conejero, Agustí Lledós
Angew. Chem. Int. Ed. 2014, 53, 14158.
Boryl-assisted hydrogenolysis of a nickel–methyl bond
Natalia Curado, Celia Maya, Joaquín López-Serrano, Amor Rodríguez
Chem. Commun. 2014, 50, 15718.
A Stable, Mononuclear, Cationic Pt(III) Complex Stabilised by Bulky N-Heterocyclic Carbenes
Pablo J. Alonso, Josefina Díez, Agustí Lledós, Salvador Conejero
Chem. Commun. 2014, 50, 1299.
Orestes Rivada-Wheelaghan, Marta Roselló-Merino, Josefina Díez, Celia Maya, Joaquín López-Serrano, Salvador Conejero
Marta Roselló-Merino, Orestes Rivada-Wheelaghan, Manuel A. Ortuño, Pietro Vidossich, Josefina Díez, Agustí Lledós, Salvador Conejero
Orestes Rivada-Wheelaghan, Marta Roselló-Merino, Manuel Ortuño, Pietro Vidossich, Enrique Gutiérrez-Puebla, Agustí Lledós, Salvador Conejero
Dehydrocoupling reactions of dimethylamine-borane by Pt(II) complexes: a new mechanism involving deprotonation of boronium cations
Marta Roselló-Merino, Joaquín López-Serrano, Salvador Conejero
J. Am. Chem. Soc. 2013,135, 10910.
Water-Soluble Gold(I) and Gold(III) Complexes with Sulfonated NHC Ligands: Synthesis, Characterization and Application in the Catalytic Cycloisomerization of γ-Alkynoic Acids into Enol-Lactones
Eder Tomás-Mendivil, Patrick Toullec, Javier Borge, Salvador Conejero, Veronique Michelet, Victorio Cadierno
ACS Catalysis 2013,3, 3086.
Characterization of a Mononuclear, Paramagnetic Pt(III)-Alkyl Complex Intermediate in Carbon-Halogen Coupling Reactions
Orestes Rivada-Wheelaghan, Manuel A. Ortuño, Josefina Díez, Sergio E. García Garrido, Celia Maya, Agustí Lledós, Salvador Conejero
J. Am. Chem. Soc. 2012, 134, 15261.
Tuning N-Heterocyclic Carbenes in T-Sahped Pt(II) Complexes for Intermolecular C-H Bond Activation of Arenes
Orestes Rivada-Wheelaghan, Manuel A. Ortuño, Josefina Díez, Agustí Lledós, Salvador Conejero
Angew. Chem. Int. Ed. 2012, 51, 3936.
Patricia Lara, Orestes Rivada-Wheelaghan, Salvador Conejero, Romual Poteau, Karine Philippot, Bruno Chaudret.
T-Shaped Platinum(II) Complexes Stabilised by Bulky N-Heterocyclic Carbene Ligands
Orestes Rivada-Wheelaghan, Bruno Donnadieu, Josefina Díez, Salvador Conejero.
A simple, general route to 2-pyridylidene transition metal complexes
Marta Roselló-Merino, Josefina Díez, Salvador Conejero.
PICTURES
The lab
Crystals of the Pt(III) complex [Pt(I)2(IPr)2][BArF]
Salva in the Ebro Foods Prize ceremony recieving Pablo Ríos prize (second accesit) for his article "Isolation of a Cationic Pt(II) σ-Silane Complex" in Angew. Chem. Int. Ed. (2018).
Pablo receiving the Ebro Foods prize (second accesit) for his article "Mechanistic Studies on the Selective Reduction of CO2 to the Aldehyde Level by a Bis(phosphino)boryl (PBP)-Supported Nickel Complex" in ACS Catalysis (2016).
Leo stretching in the glove-box
Salva at the GEQO Congress held in Zaragoza (2018)
The other lab
Feria de Abril 2024
Paco's farewell
BBQ at Orestes's house 2023
Christmas 2023
Christmas 2022
At the LAB203 terrace
Sitges 2017
FUNDING
Projects
PID2022-141925NB-I00 (9.2023-8.2026)
PID2019-109312GB-I00 (6.2020-5.2023)
CTQ2016-76267-P (12.2016-12.2019)
CTQ2013-45011-P (1.2014-12.2016)
Projects
ProyExcel_00758 (8.2022-12.2025)
P20_00513 (6.2020-12.2022)
FQM 2126 (5.2014-2.2019)
FQM 3151 (1.2008-12.2012)
Projects
2023AEP091 (6.2023-11.2023)
AEPP CTQ2016-76267-P (15.2020-12.2020)
Projects
841154 (8.19-7.22)
JOB OPPORTUNITIES
"Garantía Juvenil" PROGRAM (2022): Our group has been awarded with one contract for graduate students. If you are interested in applying with us please send us an e-mail (see contact details below). Grants will have a duration of 12 months. Check the following link: https://sepe.es/HomeSepe/Personas/encontrar-trabajo/Garantia-Juvenil/que-es-garantia-juvenil.html.
JUAN DE LA CIERVA POSTDOCTORAL GRANTS AND RAMÓN Y CAJAL TENURE CONTRACTS: We are constantly looking for people who would like to join our group through these calls. If you are interested in applying with us for a pos-doctoral contract within the Juan de la Cierva (JdC) program there are two options depending on your PhD experience:
· Juan de la Cierva Training: A 2 years contract for doctors having obtained a doctorate in the last 2 years.
· Juan de la Cierva Incorporation: A 3 years contract for doctors with previous postdoctoral training.
The Ramón y Cajal contracts are 5 years grants aimed at promoting the incorporation of national and foreign researchers with an outstanding career in R&D centers.
For incoming calls check this link:
Besides we'll be happy to host postdoctoral fellows from other programs (Marie Curie, Talentia,....)
CONTACT
Salvador Conejero: sconejero@iiq.csic.es (Phone: (+34)954 139 275)
Amor Rodríguez: marodriguez@iiq.csic.es (Phone: (+34)954 139 276)
Lab:Phone: (+34)954 139 261)
Instituto de Investigaciones Químicas
C/ Américo Vespucio 49
41092
Sevilla (Spain)